Atropine and hyoscine

Lorazepam, hyoscine and atropine as i.v. surgical premedicants.

Lorazepam 2 and 4 mg alone and in combination with atropine 0.4 mg and hyoscine 0.4 mg were studied as i.v. surgical premedicants in 150 patients. Relief of anxiety, sedation, patient acceptance, lack of recall and side-effects were evaluated. Hyoscine was found to improve the relief of anxiety and sedation associated with lorazepam, but did not significantly increase lack of recall or patient ...

Atropine or hyoscine in treatment of acute organophosphate poisoning?

The abdominal wall was infiltrated with lignocaine and incised in the mid-line. 3 litres of semisolid food was removed from the stomach and exploration revealed gross gaseous distension of small and large bowel, with infarction of the small bowel, and gas bubbles in the mesenteric veins. The ischaemic bowel was decompressed and packed with hot towels without any improvement and the patient died...

Comparative study of the effects of oral and i.m. atropine and hyoscine in volunteers.

The effects of equivalent doses of atropine and hyoscine following oral and i.m. administration were assessed on salivary secretion, heart rate, arterial pressure, body temperature, pupillary size, near-point of vision and sweat-gland activity. The ratio of oral to i.m. doses of atropine on heart rate and salivary secretion appears to be 2:1 and that of hyoscine on salivary secretion about 5-6:...

Comparison of the cognitive effects of premedication with hyoscine and atropine.

An investigation was carried out comparing the nature and duration of the cognitive effects of atropine and hyoscine. Thirty patients undergoing a minor gynaecological operation were randomly assigned to one of three groups to receive hyoscine, atropine or placebo as premedication. A battery of psychological tests was administered before premedication, 30 min after premedication, and 1 and 3 h ...

Sublingual atropine for the treatment of severe and hyoscine-resistant clozapine-induced sialorrhea.